Know Your Grant → by state → South Carolina
South Carolina grants for nonprofits & individuals
Open federal and state grants South Carolina organizations and individuals can apply for — with who qualifies, how much, the deadline, and exactly what each one requires.
State-specific South Carolina grant programs are being added; federal opportunities below are open to South Carolina applicants.
Which federal programs actually fund South Carolina
Competitively awarded federal grant dollars that went to South Carolina recipients in FY2025 — project grants and cooperative agreements only. Formula and block funding (Medicaid, highways) is excluded because it is allocated to state government, not won by applicants.
| Program | Assistance listing | Awarded in South Carolina |
|---|---|---|
| Broadband Equity, Access, and Deployment Program | 11.035 | $546.5M |
| New Empowering Rural America (New ERA) Program | 10.758 | $442.2M |
| Manufacturing and Energy Supply Chain Demonstrations and Commercial Applications | 81.253 | $285.0M |
| Highway Planning and Construction | 20.205 | $261.1M |
| Airport Improvement Program, Infrastructure Investment and Jobs Act Programs, and COVID-19 Airports Programs | 20.106 | $164.1M |
| Head Start | 93.600 | $142.9M |
| Disaster Grants - Public Assistance (Presidentially Declared Disasters) | 97.036 | $124.8M |
| Health Center Program (Community Health Centers, Migrant Health Centers, Health Care for the Homeless, and Public Housing Primary Care) | 93.224 | $96.0M |
Who won competitive federal grants in South Carolina
The largest South Carolina recipients of competitive federal grant awards in FY2025. Useful for two things: seeing who your likely co-applicants and partners are, and seeing which programs have a track record of paying out in this state.
| Recipient | Awarded |
|---|---|
| EXECUTIVE OFFICE OF THE STATE OF SOUTH CAROLINA | $559.0M |
| CENTRAL ELECTRIC POWER COOPERATIVE INC | $442.2M |
| MERCEDES-BENZ VANS, LLC | $285.0M |
| SOUTH CAROLINA DEPARTMENT OF TRANSPORTATION | $264.9M |
| THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | $145.3M |
| CLEMSON UNIVERSITY | $139.2M |
| ADJUTANT GENERAL SOUTH CAROLINA | $135.1M |
| UNIVERSITY OF SOUTH CAROLINA | $125.4M |
Open federal grants for South Carolina applicants
A sample of the 2,243 federal opportunities open now — each links to a full breakdown of eligibility, required documents, and deadlines. Listed first: the 12 whose program has a record of awarding money in South Carolina.
Not sure which you qualify for?
Tell us what you are and we'll filter to the South Carolina + federal grants you're actually eligible for.